Malaria was not found in the Americas prior to the discovery of the New World by Europeans. There was therefore even less immunity among the native populations than there was among Europeans. Due to their genetics, African slaves had greater immunity to falciparum malaria, and this was one reason why slaves were brought in great numbers from Africa.
The Caribbean countries most affected by malaria were the Greater Antilles islands and other humid islands like Martinique and Trinidad and Tobago. Anopheles mosquitoes thrive mostly in areas of humidity and fresh water, so the disease was not found on islands such as the Bahamas and Antigua.
- Esposito, Elena: “Side effects of immunities: the African slave trade” (2015). European University Institute, Max Weber Programme, Working Paper. 
- "Deyalsingh: 5 imported cases of malaria in T&T for 2019". www.looptt.com. Retrieved 2019-06-12.
- McNeill, J. R. (2010-01-11). Mosquito Empires: Ecology and War in the Greater Caribbean, 1620–1914. Cambridge University Press. ISBN 9781139484503.
- "CARPHA urges region to deal seriously to eradicate mosquitoes". May 14, 2019.